Head Coach: Don Hardin Record: 16-15 (3-3 Metro)
| Date | Site | Opponent | W/L | UL | Opp | Overall | Conf | City | Event | Type |
|---|---|---|---|---|---|---|---|---|---|---|
| 08/29/1988 | H | Western Kentucky | W | 3 | 1 | 1-0 | 0-0 | Louisville, Ky. | ||
| 09/03/1988 | N | Morehead State | L | 1 | 3 | 1-1 | 0-0 | Lexington, Ky. | ||
| 09/04/1988 | N | Eastern Kentucky | W | 3 | 2 | 2-1 | 0-0 | Lexington, Ky. | ||
| 09/07/1988 | H | Miami, Ohio | W | 3 | 0 | 3-1 | 0-0 | Louisville, Ky. | ||
| 09/09/1988 | N | Tennessee Tech | W | 3 | 1 | 4-1 | 0-0 | Bowling Green, Ky. | ||
| 09/10/1988 | N | Chattanooga | W | 3 | 0 | 5-1 | 0-0 | Bowling Green, Ky. | ||
| 09/10/1988 | N | Morehead State | L | 1 | 3 | 5-2 | 0-0 | Bowling Green, Ky. | ||
| 09/10/1988 | N | East Tennessee State | W | 3 | 0 | 6-2 | 0-0 | Bowling Green, Ky. | ||
| 09/13/1988 | H | Murray State | W | 3 | 0 | 7-2 | 0-0 | Louisville, Ky. | ||
| 09/16/1988 | H | Saint Louis | L | 0 | 3 | 7-3 | 0-0 | Louisville, Ky. | ||
| 09/16/1988 | H | Wright State | L | 1 | 3 | 7-4 | 0-0 | Louisville, Ky. | ||
| 09/20/1988 | A | Butler | L | 1 | 3 | 7-5 | 0-0 | Indianapolis, Ind. | ||
| 09/24/1988 | N | Temple | W | 3 | 0 | 8-5 | 0-0 | Philadelphia, Pa. | ||
| 09/25/1988 | A | Pennsylvania | W | 3 | 2 | 9-5 | 0-0 | Philadelphia, Pa. | ||
| 09/25/1988 | N | North Carolina | L | 0 | 3 | 9-6 | 0-0 | Louisville, Ky. | ||
| 10/01/1988 | N | Bucknell | W | 3 | 1 | 10-6 | 0-0 | Kent, Ohio | ||
| 10/01/1988 | A | Kent State | L | 0 | 3 | 10-7 | 0-0 | Kent, Ohio | ||
| 10/07/1988 | H | Memphis | L | 1 | 3 | 10-8 | 0-1 | Louisville, Ky. | Conf | |
| 10/11/1988 | A | Tennessee | L | 0 | 3 | 10-9 | 0-1 | Knoxville, Tenn. | ||
| 10/15/1988 | H | Cincinnati | L | 1 | 3 | 10-10 | 0-2 | Louisville, Ky. | Conf | |
| 10/16/1988 | H | Southern Mississippi | W | 3 | 0 | 11-10 | 1-2 | Louisville, Ky. | Conf | |
| 10/18/1988 | A | Kentucky | L | 0 | 3 | 11-11 | 1-2 | Lexington, Ky. | ||
| 10/21/1988 | A | Xavier | W | 3 | 0 | 12-11 | 1-2 | Cincinnati, Ohio | ||
| 10/25/1988 | H | Bellarmine | W | 3 | 0 | 13-11 | 1-2 | Louisville, Ky. | ||
| 10/29/1988 | A | Florida State | L | 0 | 3 | 13-12 | 1-3 | Tallahassee, Fla. | Conf | |
| 10/30/1988 | A | Florida | L | 0 | 3 | 13-13 | 1-3 | Gainesville, Fla. | ||
| 11/04/1988 | A | South Carolina | W | 3 | 0 | 14-13 | 2-3 | Columbia, S.C. | Conf | |
| 11/05/1988 | A | Virginia Tech | W | 3 | 1 | 15-13 | 3-3 | Blacksburg, Va. | Conf | |
| 11/08/1988 | H | Ball State | L | 0 | 3 | 15-14 | 3-3 | Louisville, Ky. | ||
| 11/14/1988 | H | Austin Peay | W | 3 | 0 | 16-14 | 3-3 | Louisville, Ky. | ||
| 11/18/1988 | N | Memphis | L | 0 | 3 | 16-15 | 3-3 | Cincinnati, Ohio | Metro Conference Tournament | CT |