Head Coach: Leonid Yelin Record: 25-6 (12-1 C-USA)
| Date | Site | Opp Rk | Opponent | W/L | UL | Opp | Overall | Conf | Attendance | City | Arena | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 08/29/2003 | A | 13 | UCLA | L | 0 | 3 | 0-1 | 0-0 | Honolulu, Hawaii | Stan Sheriff Center | ||
| 08/30/2003 | A | 6 | Minnesota | W | 3 | 1 | 1-1 | 0-0 | 250 | Honolulu, Hawaii | Stan Sheriff Center | |
| 08/31/2003 | A | 2 | Hawaii | L | 0 | 3 | 1-2 | 0-0 | 6,389 | Honolulu, Hawaii | Stan Sheriff Center | |
| 09/05/2003 | A | Texas A&M | L | 1 | 3 | 1-3 | 0-0 | 87 | Ann Arbor, Mich. | Cliff Keen Arena | ||
| 09/06/2003 | A | Murray State | W | 3 | 2 | 2-3 | 0-0 | 237 | Ann Arbor, Mich. | Cliff Keen Arena | ||
| 09/07/2003 | A | Michigan | W | 3 | 1 | 3-3 | 0-0 | 467 | Ann Arbor, Mich. | Cliff Keen Arena | ||
| 09/12/2003 | H | Alabama | W | 3 | 0 | 4-3 | 0-0 | Louisville, Ky. | Cardinal Arena | |||
| 09/13/2003 | H | Georgia | W | 3 | 1 | 5-3 | 0-0 | Louisville, Ky. | Cardinal Arena | |||
| 09/19/2003 | A | Wake Forest | W | 3 | 0 | 6-3 | 0-0 | Winston-Salem, N.C. | ||||
| 09/27/2003 | A | Xavier | W | 3 | 0 | 7-3 | 0-0 | Cincinnati, Ohio | ||||
| 10/03/2003 | H | DePaul | W | 3 | 0 | 8-3 | 1-0 | Louisville, Ky. | Cardinal Arena | Conf | ||
| 10/04/2003 | H | Marquette | W | 3 | 1 | 9-3 | 2-0 | 912 | Louisville, Ky. | Cardinal Arena | Conf | |
| 10/10/2003 | A | Cincinnati | L | 0 | 3 | 9-4 | 2-1 | 457 | Cincinnati, Ohio | Fifth Third Arena | Conf | |
| 10/17/2003 | A | East Carolina | W | 3 | 1 | 10-4 | 3-1 | 206 | Greenville, N.C. | Williams Arena | Conf | |
| 10/18/2003 | A | Charlotte | W | 3 | 0 | 11-4 | 4-1 | 185 | Charlotte, N.C. | Halton Arena | Conf | |
| 10/24/2003 | H | Tulane | W | 3 | 0 | 12-4 | 5-1 | 930 | Louisville, Ky. | Cardinal Arena | Conf | |
| 10/25/2003 | H | Southern Mississippi | W | 3 | 0 | 13-4 | 6-1 | 899 | Louisville, Ky. | Cardinal Arena | Conf | |
| 10/31/2003 | A | Memphis | W | 3 | 2 | 14-4 | 7-1 | 364 | Memphis, Tenn. | Elma Roane Fieldhouse | Conf | |
| 11/01/2003 | A | Saint Louis | W | 3 | 1 | 15-4 | 8-1 | 846 | St. Louis, Mo. | Bauman-Eberhardt Center | Conf | |
| 11/07/2003 | H | Texas Christian | W | 3 | 1 | 16-4 | 9-1 | 801 | Louisville, Ky. | Cardinal Arena | Conf | |
| 11/08/2003 | H | Houston | W | 3 | 0 | 17-4 | 10-1 | 980 | Louisville, Ky. | Cardinal Arena | Conf | |
| 11/10/2003 | H | Kentucky | W | 3 | 1 | 18-4 | 10-1 | 998 | Louisville, Ky. | Cardinal Arena | ||
| 11/14/2003 | A | South Florida | W | 3 | 0 | 19-4 | 11-1 | Tampa, Fla. | The Corral | Conf | ||
| 11/15/2003 | A | Alabama-Birmingham | W | 3 | 1 | 20-4 | 12-1 | 221 | Birmingham, Ala. | Bartow Arena | Conf | |
| 11/22/2003 | A | Texas Christian | W | 3 | 0 | 21-4 | 12-1 | New Orleans, La. | Fogelman Arena | CT | ||
| 11/23/2003 | A | Marquette | W | 3 | 0 | 22-4 | 12-1 | New Orleans, La. | Fogelman Arena | CT | ||
| 11/24/2003 | A | Memphis | W | 3 | 0 | 23-4 | 12-1 | 142 | New Orleans, La. | Fogelman Arena | CT | |
| 11/28/2003 | H | Western Michigan | W | 3 | 1 | 24-4 | 12-1 | 799 | Louisville, Ky. | Cardinal Arena | ||
| 11/29/2003 | H | Ball State | L | 2 | 3 | 24-5 | 12-1 | 703 | Louisville, Ky. | Cardinal Arena | ||
| 12/05/2003 | A | Notre Dame | W | 3 | 0 | 25-5 | 12-1 | Champaign, Ill. | Huff Hall | NCAA 1st Round | ||
| 12/06/2003 | A | Illinois | L | 0 | 3 | 25-6 | 12-1 | Champaign, Ill. | NCAA 2nd Round |