Head Coach: Dan Meske Record: 22-2 (12-0 ACC)
| Date | Site | Opp Rk | Opponent | W/L | UL | Opp | Overall | Conf | Attendance | City | Arena | Event | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 08/21/2026 | N | 8 | Texas A&M | W | 3 | 1 | 1-0 | 0-0 | 6,345 | Milwaukee, Wis. | Fiserv Forum | AVCA First Serve | |
| 08/22/2026 | N | 6 | Wisconsin | L | 0 | 3 | 1-1 | 0-0 | 7,618 | Milwaukee, Wis. | Fiserv Forum | AVCA First Serve | |
| 08/28/2026 | H | 16 | Indiana | W | 3 | 0 | 2-1 | 0-0 | 1,074 | Louisville, Ky. | L&N Federal Credit Union Arena | ||
| 08/31/2026 | H | Dayton | W | 3 | 0 | 3-1 | 0-0 | 1,055 | Louisville, Ky. | L&N Federal Credit Union Arena | |||
| 09/04/2026 | H | 18 | Texas Christian | W | 3 | 0 | 4-1 | 0-0 | 1,074 | Louisville, Ky. | L&N Federal Credit Union Arena | ||
| 09/06/2026 | N | 9 | Texas | W | 3 | 0 | 5-1 | 0-0 | Nashville, Tenn. | Bridgestone Arena | Broadway Block Party | ||
| 09/09/2026 | H | Missouri | W | 3 | 1 | 6-1 | 0-0 | 5,076 | Louisville, Ky. | KFC Yum! Center | Showdown at the Net | ||
| 09/11/2026 | A | Rice | W | 3 | 1 | 7-1 | 0-0 | 927 | Houston, Texas | Tudor Fieldhouse | Rice Invitational | ||
| 09/12/2026 | N | 15 | Creighton | W | 3 | 1 | 8-1 | 0-0 | 557 | Houston, Texas | Tudor Fieldhouse | Rice Invitational | |
| 09/13/2026 | N | Northern Iowa | W | 3 | 0 | 9-1 | 0-0 | 529 | Houston, Texas | Tudor Fieldhouse | Rice Invitational | ||
| 09/16/2026 | A | Western Kentucky | W | 3 | 0 | 10-1 | 0-0 | 2,681 | Bowling Green, Ky. | E.A. Diddle Arena | |||
| 09/20/2026 | A | 4 | Kentucky | L | 1 | 3 | 10-2 | 0-0 | 6,045 | Lexington, Ky. | Historic Memorial Coliseum | ||
| 09/25/2026 | A | Syracuse | W | 3 | 0 | 11-2 | 1-0 | 201 | Syracuse, N.Y. | Women's Building | Conf | ||
| 09/27/2026 | A | Boston College | W | 3 | 0 | 12-2 | 2-0 | 832 | Chestnut Hill, Mass. | Connell Recreation Center | Conf | ||
| 09/30/2026 | H | Notre Dame | W | 3 | 0 | 13-2 | 3-0 | 1,072 | Louisville, Ky. | L&N Federal Credit Union Arena | Conf | ||
| 10/03/2026 | A | Notre Dame | W | 3 | 0 | 14-2 | 4-0 | 944 | South Bend, Ind. | Purcell Pavilion at the Joyce Center | Conf | ||
| 10/08/2026 | H | California | W | 3 | 1 | 15-2 | 5-0 | 1,045 | Louisville, Ky. | L&N Federal Credit Union Arena | Conf | ||
| 10/11/2026 | H | 14 | Stanford | W | 3 | 0 | 16-2 | 6-0 | 1,050 | Louisville, Ky. | L&N Federal Credit Union Arena | Conf | |
| 10/16/2026 | H | Duke | W | 3 | 0 | 17-2 | 7-0 | 1,074 | Louisville, Ky. | L&N Federal Credit Union Arena | Conf | ||
| 10/18/2026 | H | 23 | North Carolina | W | 3 | 0 | 18-2 | 8-0 | 1,054 | Louisville, Ky. | L&N Federal Credit Union Arena | Conf | |
| 10/23/2026 | A | Florida State | W | 3 | 0 | 19-2 | 9-0 | 725 | Tallahassee, Fla. | Tully Gymnasium | Conf | ||
| 10/25/2026 | A | Miami, Fla. | W | 3 | 1 | 20-2 | 10-0 | 1,157 | Coral Gables, Fla. | Freeman Indoor Stadium at the Knight Sports Complex | Conf | ||
| 10/30/2026 | H | Clemson | W | 3 | 0 | 21-2 | 11-0 | 1,043 | Louisville, Ky. | L&N Federal Credit Union Arena | Conf | ||
| 11/01/2026 | H | Georgia Tech | W | 3 | 0 | 22-2 | 12-0 | 6,873 | Louisville, Ky. | KFC Yum! Center | Conf |