Head Coach: Dani Busboom Kelly Record: 30-6 (17-3 ACC)
| Date | Site | Opp Rk | Opponent | W/L | UL | Opp | Overall | Conf | Attendance | City | Arena | Event | Type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 08/27/2024 | H | 3 | Wisconsin | W | 3 | 1 | 1-0 | 0-0 | 9,280 | Louisville, Ky. | L&N Federal Credit Union Arena | AVCA First Serve Showcase | |
| 09/01/2024 | H | 15 | Tennessee | W | 3 | 0 | 2-0 | 0-0 | 7,571 | Louisville, Ky. | L&N Federal Credit Union Arena | ||
| 09/03/2024 | A | 7 | Penn State | L | 0 | 3 | 2-1 | 0-0 | 3,865 | University Park, Pa. | Rec Hall | ||
| 09/06/2024 | N | South Dakota | W | 3 | 1 | 3-1 | 0-0 | 125 | Highland Heights, Ky. | Regents Hall | Northern Kentucky University Tournament | ||
| 09/07/2024 | N | Missouri | W | 3 | 0 | 4-1 | 0-0 | 242 | Highland Heights, Ky. | Regents Hall | Northern Kentucky University Tournament | ||
| 09/08/2024 | A | Northern Kentucky | W | 3 | 0 | 5-1 | 0-0 | 703 | Highland Heights, Ky. | Regents Hall | Northern Kentucky University Tournament | ||
| 09/14/2024 | H | Northern Iowa | W | 3 | 0 | 6-1 | 0-0 | 5,608 | Louisville, Ky. | L&N Federal Credit Union Arena | Cardinal Classic | ||
| 09/15/2024 | H | 9 | Creighton | W | 3 | 2 | 7-1 | 0-0 | 5,970 | Louisville, Ky. | L&N Federal Credit Union Arena | Cardinal Classic | |
| 09/18/2024 | A | 11 | Kentucky | W | 3 | 1 | 8-1 | 0-0 | 3,838 | Lexington, Ky. | Rupp Arena | ||
| 09/22/2024 | H | 5 | Nebraska | L | 0 | 3 | 8-2 | 0-0 | 14,126 | Louisville, Ky. | L&N Federal Credit Union Arena | ||
| 09/27/2024 | H | California | W | 3 | 0 | 9-2 | 1-0 | 1,000 | Louisville, Ky. | L&N Federal Credit Union Arena | Conf | ||
| 09/29/2024 | H | 2 | Stanford | W | 3 | 0 | 10-2 | 2-0 | 7,898 | Louisville, Ky. | L&N Federal Credit Union Arena | Conf | |
| 10/04/2024 | H | Clemson | W | 3 | 0 | 11-2 | 3-0 | 1,060 | Louisville, Ky. | L&N Federal Credit Union Arena | Conf | ||
| 10/06/2024 | H | 19 | Georgia Tech | W | 3 | 0 | 12-2 | 4-0 | 1,040 | Louisville, Ky. | L&N Federal Credit Union Arena | Conf | |
| 10/11/2024 | A | 21 | Florida State | W | 3 | 2 | 13-2 | 5-0 | 1,000 | Tallahassee, Fla. | Tully Gymnasium | Conf | |
| 10/13/2024 | A | Miami, Fla. | W | 3 | 1 | 14-2 | 6-0 | 950 | Coral Gables, Fla. | James L. Knight Sports Complex | Conf | ||
| 10/18/2024 | H | Wake Forest | W | 3 | 0 | 15-2 | 7-0 | 1,063 | Louisville, Ky. | L&N Federal Credit Union Arena | Conf | ||
| 10/20/2024 | H | North Carolina State | W | 3 | 0 | 16-2 | 8-0 | 1,041 | Louisville, Ky. | L&N Federal Credit Union Arena | Conf | ||
| 10/25/2024 | A | 1 | Pittsburgh | L | 2 | 3 | 16-3 | 8-1 | 11,309 | Pittsburgh, Pa. | Fitzgerald Field House | Conf | |
| 10/27/2024 | A | 12 | Southern Methodist | W | 3 | 1 | 17-3 | 9-1 | 3,015 | Dallas, Texas | Moody Coliseum | Conf | |
| 10/30/2024 | H | Notre Dame | W | 3 | 0 | 18-3 | 10-1 | 1,063 | Louisville, Ky. | L&N Federal Credit Union Arena | Conf | ||
| 11/02/2024 | A | Notre Dame | W | 3 | 0 | 19-3 | 11-1 | 2,339 | South Bend, Ind. | Purcell Pavilion at the Joyce Center | Conf | ||
| 11/08/2024 | A | Syracuse | W | 3 | 0 | 20-3 | 12-1 | 823 | Syracuse, N.Y. | Women's Building | Conf | ||
| 11/10/2024 | A | Boston College | W | 3 | 0 | 21-3 | 13-1 | 731 | Chestnut Hill, Mass. | Connell Recreation Center | Conf | ||
| 11/15/2024 | H | Duke | W | 3 | 0 | 22-3 | 14-1 | 1,063 | Louisville, Ky. | L&N Federal Credit Union Arena | Conf | ||
| 11/17/2024 | H | North Carolina | W | 3 | 0 | 23-3 | 15-1 | 1,041 | Louisville, Ky. | L&N Federal Credit Union Arena | Conf | ||
| 11/22/2024 | A | Virginia | W | 3 | 1 | 24-3 | 16-1 | 1,122 | Charlottesville, Va. | Memorial Gymnasium | Conf | ||
| 11/24/2024 | A | Virginia Tech | W | 3 | 0 | 25-3 | 17-1 | 480 | Blacksburg, Va. | Cassell Coliseum | Conf | ||
| 11/27/2024 | H | 1 | Pittsburgh | L | 1 | 3 | 25-4 | 17-2 | 12,510 | Louisville, Ky. | L&N Federal Credit Union Arena | Conf | |
| 11/30/2024 | A | 7 | Stanford | L | 1 | 3 | 25-5 | 17-3 | 5,673 | Stanford, Calif. | Maples Pavilion | Conf | |
| 12/06/2024 | H | Chicago State | W | 3 | 0 | 26-5 | 17-3 | 4,416 | Louisville, Ky. | KFC Yum! Center | NCAA Volleyball Championship | NCAA 1st Round | |
| 12/07/2024 | H | Northern Iowa | W | 3 | 2 | 27-5 | 17-3 | 4,399 | Louisville, Ky. | KFC Yum! Center | NCAA Volleyball Championship | NCAA 2nd Round | |
| 12/12/2024 | H | Purdue | W | 3 | 0 | 28-5 | 17-3 | 4,706 | Louisville, Ky. | Freedom Hall | NCAA Volleyball Championship | NCAA Regional Semifinal | |
| 12/14/2024 | H | Stanford | W | 3 | 1 | 29-5 | 17-3 | 5,284 | Louisville, Ky. | Freedom Hall | NCAA Volleyball Championship | NCAA Regional Final | |
| 12/19/2024 | N | Pittsburgh | W | 3 | 1 | 30-5 | 17-3 | Louisville, Ky. | KFC Yum! Center | NCAA Volleyball Championship | NCAA National Semifinal | ||
| 12/22/2024 | H | 1 | Penn State | L | 1 | 3 | 30-6 | 17-3 | 21,860 | Louisville, Ky. | KFC Yum! Center | NCAA Volleyball Championship | NCAA National Final |